Exo III

Exo III

年级
GMP级别
SKU: ON-911
单价:
$0.00
价格
$0.00
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详情

产品信息

核酸外切酶 III,又称 Exo III,具有 3'-5' 脱氧核糖核酸外切酶活性,可从平末端、5' 突出端或切口处消化双链 DNA (dsDNA) 的一条链,释放 5'-单核苷酸并产生单链 DNA (ssDNA) 片段。Exo III 对长度为 4 个或更多碱基的 3' 突出端、ssDNA 或硫酯连接的核苷酸不具活性。它还具有 3'-磷酸酶活性、RNase H 活性和脱嘌呤/脱嘧啶核酸内切酶活性。

规格

  • 目录号
    ON-911
  • 来源
    重组大肠杆菌
  • 纯度
    SDS-PAGE 检测纯度>95%
  • 储存条件
    零下20摄氏度

文档

产品信息

核酸外切酶 III,又称 Exo III,具有 3'-5' 脱氧核糖核酸外切酶活性,可从平末端、5' 突出端或切口处消化双链 DNA (dsDNA) 的一条链,释放 5'-单核苷酸并产生单链 DNA (ssDNA) 片段。Exo III 对长度为 4 个或更多碱基的 3' 突出端、ssDNA 或硫酯连接的核苷酸不具活性。它还具有 3'-磷酸酶活性、RNase H 活性和脱嘌呤/脱嘧啶核酸内切酶活性。

Why choose Hongene?

Trusted Partner in Nucleic Acid

Enjoy enterprise‑grade quality even with small batch orders.

Integrated Supply & Commercial Scale

With nearly 30 years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

Proprietary Technology & IP

Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

Rigorous Quality

We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates a 1.67-million-square-foot oligonucleotide manufacturing facility featuring advanced equipment, including multiple OligoPilot™ and OligoProcess™ synthesizers ranging from 10 to 1,800 mmol. Its 48 flexible production lines enable seamless, one-stop scale-up of API production from gram-level quantities to metric tons, achieving purity of ≥98% while supporting compliance with NMPA, FDA, and EMA regulatory requirements.

Global Business Network

Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

Global Business Distribution
40+
Countries & Regions
≈3000
Global Clients
54000L+
Annual NTP Production
58t+
Annual Amidites Production