UTP, 100mM solution

Uridine-5'-triphosphate, trisodium salt

Catalog No.	R5331
CAS No.	19817-92-6
Purity	HPLC ≥99%
Molecular Formula	C₉H₁₂N₂Na₃O₁₅P₃
Molecular Weight	550.09
Storage Condition	Long term (Infrequent use; 1-2 times per month): -70℃. Daily/Weekly use: -20℃

UTP, 100mM solution

Uridine-5'-triphosphate, trisodium salt

Grade

M (Molecular Biology) S (Endotoxin)

Amount/Package: 1mL / centrifuge tube

1mL / centrifuge tube

5mL / nalgene bottle

产品变体

SKU： R5331-ML001-P

Collections: 信使RNA（mRNA）其他原料合成砌块核苷三磷酸（NTP）核苷酸用于 mRNA合成的核苷酸诊断

Price

$17.50

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Details

尿苷 5'‑三磷酸（UTP）是 RNA 合成的底物，同时也是糖基化途径中多种核苷酸‑糖衍生物的前体。

本品为 100 mM 三钠盐溶液，以高溶解度、即用型形式提供 UTP，适用于常规实验室应用和高一致性生产环境。

应用

参考标准品与质控品

用作 HPLC、LC‑MS、酶动力学及核苷酸定量检测校准的定量标准品。

转录与 RNA 合成

用于 mRNA、sgRNA、核酶及结构化 RNA 合成的体外转录。

细胞信号传导与受体生物学

涉及 UTP 响应的 P2Y 受体的嘌呤能信号传导研究。^[1][2]

特点与优势

高纯度（≥99%）、无核酸酶、超低内毒素：适用于灵敏的生化检测。

即用型：100 mM 溶液省去了称量和溶解步骤。

稳定的二钠盐形式：确保一致的 pH 和长期储存稳定性。

参考文献

[1] Stucky, Cheryl L., Karen A. Medler, and Derek C. Molliver. "The P2Y agonist UTP activates cutaneous afferent fibers." Pain 109, no. 1-2 (2004): 36-44. [2] Choi, Roy CY, Glanice KY Chu, Nina L. Siow, Amanda WY Yung, Lisa Y. Yung, Pinky SC Lee, Christopher CW Lo et al. "Activation of UTP-sensitive P2Y2 receptor induces the expression of cholinergic genes in cultured cortical neurons: a signaling cascade triggered by Ca2+ mobilization and extracellular regulated kinase phosphorylation." Molecular Pharmacology 84, no. 1 (2013): 50-61.

规格

Catalog No.

R5331
R5331
R5-047
CAS No.

19817-92-6
19817-92-6
19817-92-6
SMILES

O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
Molecular Formula

C₉H₁₂N₂Na₃O₁₅P₃
C₉H₁₂N₂Na₃O₁₅P₃
C₉H₁₂N₂Na₃O₁₅P₃
Molecular Weight

550.09
550.09
550.09
Appearance

Clear colorless solution
Clear colorless solution
Clear colorless solution
Purity

HPLC ≥99%
HPLC ≥99%
HPLC ≥99%
Storage Condition

Long term (Infrequent use; 1-2 times per month): -70℃. Daily/Weekly use: -20℃
Long term (Infrequent use; 1-2 times per month): -70℃. Daily/Weekly use: -20℃
Long term (Infrequent use; 1-2 times per month): -70℃. Daily/Weekly use: -20℃
Quality Control

This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.

Documentation

COA 联系我们

尿苷 5'‑三磷酸（UTP）是 RNA 合成的底物，同时也是糖基化途径中多种核苷酸‑糖衍生物的前体。

本品为 100 mM 三钠盐溶液，以高溶解度、即用型形式提供 UTP，适用于常规实验室应用和高一致性生产环境。

应用

参考标准品与质控品

用作 HPLC、LC‑MS、酶动力学及核苷酸定量检测校准的定量标准品。

转录与 RNA 合成

用于 mRNA、sgRNA、核酶及结构化 RNA 合成的体外转录。

细胞信号传导与受体生物学

涉及 UTP 响应的 P2Y 受体的嘌呤能信号传导研究。^[1][2]

特点与优势

高纯度（≥99%）、无核酸酶、超低内毒素：适用于灵敏的生化检测。

即用型：100 mM 溶液省去了称量和溶解步骤。

稳定的二钠盐形式：确保一致的 pH 和长期储存稳定性。

参考文献

Catalog No.

R5331
R5331
R5-047
CAS No.

19817-92-6
19817-92-6
19817-92-6
SMILES

O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
Molecular Formula

C₉H₁₂N₂Na₃O₁₅P₃
C₉H₁₂N₂Na₃O₁₅P₃
C₉H₁₂N₂Na₃O₁₅P₃
Molecular Weight

550.09
550.09
550.09
Appearance

Clear colorless solution
Clear colorless solution
Clear colorless solution
Purity

HPLC ≥99%
HPLC ≥99%
HPLC ≥99%
Storage Condition

Long term (Infrequent use; 1-2 times per month): -70℃. Daily/Weekly use: -20℃
Long term (Infrequent use; 1-2 times per month): -70℃. Daily/Weekly use: -20℃
Long term (Infrequent use; 1-2 times per month): -70℃. Daily/Weekly use: -20℃
Quality Control

This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.

Why choose Hongene?

Trusted Partner in Nucleic Acid

Enjoy enterprise‑grade quality even with small batch orders.

Integrated Supply & Commercial Scale

With nearly 30 years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

Proprietary Technology & IP

Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

Rigorous Quality

We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates a 1.67-million-square-foot oligonucleotide manufacturing facility featuring advanced equipment, including multiple OligoPilot™ and OligoProcess™ synthesizers ranging from 10 to 1,800 mmol. Its 48 flexible production lines enable seamless, one-stop scale-up of API production from gram-level quantities to metric tons, achieving purity of ≥98% while supporting compliance with NMPA, FDA, and EMA regulatory requirements.

Global Business Network

Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

Global Business Distribution

40+

Countries & Regions

≈3000

Global Clients

54000L+

Annual NTP Production

58t+

Annual Amidites Production