Hongene Biotech offers end-to-end mRNA development and manufacturing services, supporting clients from plasmid design to vialed drug product. Key highlights include:
- Accelerated Development: Integrated services from plasmid to finished product.
- Fully Integrated Supply Chain: In-house raw material production ensures quality control.
- 25+ Years of RNA Expertise: Experienced team and streamlined workflows.
- State-of-the-Art Facilities: Over 30,000 sq ft of GMP-compliant labs and manufacturing space.
- On-Site Analytical Services: Rigorous testing for purity, potency, and safety.
Core Capabilities:
- mRNA Synthesis & Purification: IVT, capping, poly(A) tailing, purification, scalable from 1 mg to 100 g/batch.
- High-Quality Output: >98% full-length mRNA, dsRNA < 0.01%, capping efficiency 95–99%.
- Platform Versatility: Supports linear mRNA, circRNA, saRNA.
- LNP Encapsulation: cGMP-compliant, high encapsulation efficiency (<99%), scalable from 1 mg to 50 g.
- Fill & Finish: Automatic aseptic filling for liquid/lyophilized products, compliant with CN/US/EU GMP.
- Global Presence: Offices in Shanghai, Boston, Hamburg, and Tokyo.
(For more details, download the PDF, or visit our mRNA CDMO services page)