GMP, 100mM disodium salt solution

Guanosine-5'-monophosphate, 100 mM disodium salt solution
Catalog No. R21312
Purity HPLC≥98.0%
Molecular Formula C10H12N5Na2O8P
Molecular Weight 407.19
Storage Condition <-20℃
Endotoxin <1 EU/ml

GMP, 100mM disodium salt solution

Guanosine-5'-monophosphate, 100 mM disodium salt solution
Grade
Amount/Package: 1mL / centrifuge tube
SKU: R21312-ML001-P
Collections:  mRNA NMP Nucleotides Nucleotides for mRNA Other Raw Materials Synthesis Blocks
Unit price:
$55.00

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    Details

    Guanosine-5’-monophosphate (GMP) is a naturally occurring ribonucleotide composed of guanine, ribose, and a single 5’-phosphate group.

    GMP serves as a key biochemical building block in RNA metabolism, enzymatic reactions, and biosynthesis studies.

    This 100 mM disodium salt solution provides GMP in a highly soluble, ready-to-use form suitable for both routine laboratory applications and high-consistency manufacturing environments.

    Applications

    Enzymatic & Biochemical Research

    Acts as a substrate or regulator in studies involving nucleotide biosynthesis, RNA polymerases, phosphotransfer enzymes, and signal-transduction pathways.[1]

    Reference Standards & Controls

    Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.[2]

    Features and Benefits

    High purity(≥97%), nuclease-free, and Ultra-low endotoxin: suitable for sensitive biochemical assays.
    Ready-to-use: 100 mM solution eliminates the need for weighing and dissolution.
    Stable disodium salt form: ensures consistent pH and long-term storage.

    Reference

    [1] Staeben, Matt, Karen M. Kleman-Leyer, Andrew L. Kopp, Thane A. Westermeyer, and Robert G. Lowery. "Development and validation of a transcreener assay for detection of AMP-and GMP-producing enzymes." Assay and drug development technologies 8, no. 3 (2010): 339-350. [2] Kvitvang, Hans FN, Kåre A. Kristiansen, and Per Bruheim. "Assessment of capillary anion exchange ion chromatography tandem mass spectrometry for the quantitative profiling of the phosphometabolome and organic acids in biological extracts." Journal of Chromatography A 1370 (2014): 70-79.

    Specifications
    • Catalog No.
      R21312
    • SMILES
      O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(O[Na])(O[Na])=O)O3)=C2N=C(N)N1
    • Molecular Formula
      C10H12N5Na2O8P
    • Molecular Weight
      407.19
    • Appearance
      Clear colorless solution
    • Purity
      HPLC≥98.0%
    • Storage Condition
      <-20℃
    • Bacterial Endotoxin Test
      <1 EU/ml
    • Quality Control
      This preparation is free of DNase and RNase contamination.

    Documentation
    COA Contact Us

    Guanosine-5’-monophosphate (GMP) is a naturally occurring ribonucleotide composed of guanine, ribose, and a single 5’-phosphate group.

    GMP serves as a key biochemical building block in RNA metabolism, enzymatic reactions, and biosynthesis studies.

    This 100 mM disodium salt solution provides GMP in a highly soluble, ready-to-use form suitable for both routine laboratory applications and high-consistency manufacturing environments.

    Applications

    Enzymatic & Biochemical Research

    Acts as a substrate or regulator in studies involving nucleotide biosynthesis, RNA polymerases, phosphotransfer enzymes, and signal-transduction pathways.[1]

    Reference Standards & Controls

    Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.[2]

    Features and Benefits

    High purity(≥97%), nuclease-free, and Ultra-low endotoxin: suitable for sensitive biochemical assays.
    Ready-to-use: 100 mM solution eliminates the need for weighing and dissolution.
    Stable disodium salt form: ensures consistent pH and long-term storage.

    Reference

    [1] Staeben, Matt, Karen M. Kleman-Leyer, Andrew L. Kopp, Thane A. Westermeyer, and Robert G. Lowery. "Development and validation of a transcreener assay for detection of AMP-and GMP-producing enzymes." Assay and drug development technologies 8, no. 3 (2010): 339-350. [2] Kvitvang, Hans FN, Kåre A. Kristiansen, and Per Bruheim. "Assessment of capillary anion exchange ion chromatography tandem mass spectrometry for the quantitative profiling of the phosphometabolome and organic acids in biological extracts." Journal of Chromatography A 1370 (2014): 70-79.

    Why choose Hongene?

    Trusted Partner in Nucleic Acid

    Enjoy enterprise‑grade quality even with small batch orders.

    Integrated Supply & Commercial Scale

    With nearly 30 years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

    Proprietary Technology & IP

    Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

    Rigorous Quality

    We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

    Manufacturing Scalability

    Hongene operates a 1.67-million-square-foot oligonucleotide manufacturing facility featuring advanced equipment, including multiple OligoPilot™ and OligoProcess™ synthesizers ranging from 10 to 1,800 mmol. Its 48 flexible production lines enable seamless, one-stop scale-up of API production from gram-level quantities to metric tons, achieving purity of ≥98% while supporting compliance with NMPA, FDA, and EMA regulatory requirements.

    Global Business Network

    Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

    Global Business Distribution
    40+
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    54000L+
    Annual NTP Production
    58t+
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