GMP, 100mM disodium salt solution

Guanosine-5'-monophosphate, 100 mM disodium salt solution
Catalog No. R21312
Purity HPLC≥98%
Molecular Formula C10H12N5Na2O8P
Molecular Weight 407.19
Storage Condition -20℃
Endotoxin <1 EU/ml

GMP, 100mM disodium salt solution

Guanosine-5'-monophosphate, 100 mM disodium salt solution
Grade
Amount/Package: 1mL / centrifuge tube
SKU: R21312-ML001-P
Collections:  mRNA NMP Nucleotides Nucleotides for mRNA Other Raw Materials Synthesis Blocks
Unit price:
$55.00

Price

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Details

Guanosine-5’-monophosphate (GMP) is a naturally occurring ribonucleotide composed of guanine, ribose, and a single 5’-phosphate group.

GMP serves as a key biochemical building block in RNA metabolism, enzymatic reactions, and biosynthesis studies.

This 100 mM disodium salt solution provides GMP in a highly soluble, ready-to-use form suitable for both routine laboratory applications and high-consistency manufacturing environments.

Applications

Enzymatic & Biochemical Research

Acts as a substrate or regulator in studies involving nucleotide biosynthesis, RNA polymerases, phosphotransfer enzymes, and signal-transduction pathways.[1]

Reference Standards & Controls

Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.[2]

Features and Benefits

High purity(≥97%), nuclease-free, and Ultra-low endotoxin: suitable for sensitive biochemical assays.
Ready-to-use: 100 mM solution eliminates the need for weighing and dissolution.
Stable disodium salt form: ensures consistent pH and long-term storage.

Reference

[1] Staeben, Matt, Karen M. Kleman-Leyer, Andrew L. Kopp, Thane A. Westermeyer, and Robert G. Lowery. "Development and validation of a transcreener assay for detection of AMP-and GMP-producing enzymes." Assay and drug development technologies 8, no. 3 (2010): 339-350. [2] Kvitvang, Hans FN, Kåre A. Kristiansen, and Per Bruheim. "Assessment of capillary anion exchange ion chromatography tandem mass spectrometry for the quantitative profiling of the phosphometabolome and organic acids in biological extracts." Journal of Chromatography A 1370 (2014): 70-79.

Specifications
  • Catalog No.
    R21312
  • SMILES
    O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(O[Na])(O[Na])=O)O3)=C2N=C(N)N1
  • Molecular Formula
    C10H12N5Na2O8P
  • Molecular Weight
    407.19
  • Appearance
    Clear colorless solution
  • Purity
    HPLC≥98%
  • Storage Condition
    -20℃
  • Bacterial Endotoxin Test
    <1 EU/ml
  • Quality Control
    This preparation is free of DNase and RNase contamination.

Documentation
COA Contact Us

Guanosine-5’-monophosphate (GMP) is a naturally occurring ribonucleotide composed of guanine, ribose, and a single 5’-phosphate group.

GMP serves as a key biochemical building block in RNA metabolism, enzymatic reactions, and biosynthesis studies.

This 100 mM disodium salt solution provides GMP in a highly soluble, ready-to-use form suitable for both routine laboratory applications and high-consistency manufacturing environments.

Applications

Enzymatic & Biochemical Research

Acts as a substrate or regulator in studies involving nucleotide biosynthesis, RNA polymerases, phosphotransfer enzymes, and signal-transduction pathways.[1]

Reference Standards & Controls

Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.[2]

Features and Benefits

High purity(≥97%), nuclease-free, and Ultra-low endotoxin: suitable for sensitive biochemical assays.
Ready-to-use: 100 mM solution eliminates the need for weighing and dissolution.
Stable disodium salt form: ensures consistent pH and long-term storage.

Reference

[1] Staeben, Matt, Karen M. Kleman-Leyer, Andrew L. Kopp, Thane A. Westermeyer, and Robert G. Lowery. "Development and validation of a transcreener assay for detection of AMP-and GMP-producing enzymes." Assay and drug development technologies 8, no. 3 (2010): 339-350. [2] Kvitvang, Hans FN, Kåre A. Kristiansen, and Per Bruheim. "Assessment of capillary anion exchange ion chromatography tandem mass spectrometry for the quantitative profiling of the phosphometabolome and organic acids in biological extracts." Journal of Chromatography A 1370 (2014): 70-79.

Why choose Hongene?

Trusted Partner in Nucleic Acid

Integrated Supply & Commercial Scale

With 26+ years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

Proprietary Technology & IP

Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

Rigorous Quality

We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.

Global Business Network

Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

Global Business Distribution
40+
Countries & Regions
3000≈
Global Clients
54000+L
Annual NTP Production
58+t
Annual Amidites Production

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