5'-O-DMT-2'-O-TBDMS-N1-Me-pU Phosphoramidite

5'-O-(4, 4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-N1-methyl-Pseudouridine-3'-cyanoethyl Phosphoramidite
Catalog No. OP-031
CAS No. 875302-45-7
Purity HPLC≥98.0%
Molecular Formula C46H63N4O9PSi
Molecular Weight 875.07
Storage Condition -20℃

5'-O-DMT-2'-O-TBDMS-N1-Me-pU Phosphoramidite

5'-O-(4, 4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-N1-methyl-Pseudouridine-3'-cyanoethyl Phosphoramidite
Grade
SKU: OP-031
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Specifications

  • Catalog No.
    OP-031
  • CAS No.
    875302-45-7
  • SMILES
    C[Si](C)(C(C)(C)C)O[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)C4=CC=C(OC)C=C4)O[C@H]1C5=CN(C)C(NC5=O)=O
  • Molecular Formula
    C46H63N4O9PSi
  • Molecular Weight
    875.07
  • Appearance
    White, off-white to faint yellow powder, free from visible foreign matter
  • Purity
    HPLC≥98.0%
  • Storage Condition
    -20℃

Documentation

  • Catalog No.
    OP-031
  • CAS No.
    875302-45-7
  • SMILES
    C[Si](C)(C(C)(C)C)O[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)C4=CC=C(OC)C=C4)O[C@H]1C5=CN(C)C(NC5=O)=O
  • Molecular Formula
    C46H63N4O9PSi
  • Molecular Weight
    875.07
  • Appearance
    White, off-white to faint yellow powder, free from visible foreign matter
  • Purity
    HPLC≥98.0%
  • Storage Condition
    -20℃

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Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

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We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.

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