HG CPG™ Solid Support

This brochure introduces Hongene Biotech's HG CPG™ solid supports for end-to-end oligonucleotide synthesis, covering manufacturing advantages, specifications, loading capacities, product portfolio, and synthesis performance data.

Summary:

• Positioning: HG CPG™ solid supports are designed for oligonucleotide synthesis, with full oversight from raw glass to loaded CPG products to support quality and cost control.
• Quality and compliance: Products are rigorously tested for synthesis performance and can also be used for cGMP oligonucleotide manufacturing.
• Specifications: Available in 500 Å, 1000 Å, and 2000 Å pore sizes; particle size 120–200 μm; pore volume ≥0.8 cc/g; specific surface area ≥75, ≥25, and ≥25 m²/g respectively; pore sizes approximately 530±30, 1050±50, and 2000±100 Å.
• Loading capacity: CPG-500Å at 40–60 / 60–80 / 80+ μmol/g; CPG-1000Å at 25–40 / 40–50 μmol/g; CPG-2000Å at 25–40 μmol/g. Products can also be delivered in standard synthesis columns, plates, and frits.
• Product portfolio: Nucleoside CPGs for DNA, RNA, 2′-F, 2′-OMe, 2′-O-MOE, LNA, Reverse DNA, and Abasic; modifier CPGs such as GalNAc, Gal3, and C2; linker CPGs including Cholesterol-TEG, Tocopherol-TEG, 3′-C7 series, and DCA/EHA/EPA; functional modifier CPGs; dye and quencher CPGs; universal linker CPGs with N-iPr, N-Me, and N-Ph; custom loaded CPG inquiries are welcome.
• Performance data: The brochure includes functional loading and FLP data for GalNAc- and N-Ph universal linker-loaded HG CPG™ at 500/1000/2000 Å; testing was performed on Mermade12 with all 2′-OMe units.
• Contact information: Offices in the USA, Japan, Shanghai, and Germany are listed.

To explore the full HG CPG™ selection guide, custom loading and packaging options, or to arrange sample evaluation, please download the complete product brochure and connect with the Hongene team.