Oligonucleotide and mRNA manufacturing infrastructure

Capacity and supply chain security built for global delivery

Hongene Biotech’s RNA-focused state-of-the-art manufacturing sites provide the capacity, resilience, and quality required to support customers worldwide. Our infrastructure is designed to advance oligonucleotide and mRNA programs seamlessly — from early development through to commercial supply.

Manufacturing

  • Shanghai (2012): ISO-certified production of phosphoramidites, GalNAc, NTPs and cap analogs
  • Shanghai (2020): Expanded capacity for ISO-certified raw materials
  • Shanghai (2021): GMP mRNA CDMO services for DS, LNP formulation and fill-finish
  • Shanghai (2024): GMP oligonucleotide CDMO services for DS and DP
  • Hungary (2027): European GMP oligonucleotide CDMO services and ISO-certified raw materials

Global distribution

  • North America (San Francisco): R&D center, warehouse and client support hub
  • EMEA (Hamburg): Regional warehouse ensuring secure European supply

Commercial

  • Shanghai (2012): ISO-certified production of phosphoramidites, GalNAc, NTPs and cap analogs

Main Facilities in USA

Main Facilities in China

Other Distributions

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