2'-O-4'-C-Locked-G(iBu)-CE Phosphoramidite

N2-isobutyryl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-4'-C-Locked-Guanosine-3'-cyanoethyl Phosphoramidite
Catalog No. PR2-003
Purity HPLC≥98.0%
Molecular Formula C45H54N7O9P
Molecular Weight 867.93
Storage Condition -20℃

2'-O-4'-C-Locked-G(iBu)-CE Phosphoramidite

N2-isobutyryl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-4'-C-Locked-Guanosine-3'-cyanoethyl Phosphoramidite
Grade
SKU: PR2-003
Collections:  2'-O-4'-C Locked-NA Phosphoramidites Oligo Synthesis Phosphoramidites Synthesis Blocks
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Related Products

Specifications
  • Catalog No.
    PR2-003
  • SMILES
    O=C1C(N=CN2[C@H]3[C@H](OC4)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@]4(COC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)O3)=C2N=C(NC(C(C)C)=O)N1
  • Molecular Formula
    C45H54N7O9P
  • Molecular Weight
    867.93
  • Appearance
    Off-white to yellow powder,free from visible foreign matter
  • Purity
    HPLC≥98.0%
  • Storage Condition
    -20℃

Documentation
COA Contact Us
  • Catalog No.
    PR2-003
  • SMILES
    O=C1C(N=CN2[C@H]3[C@H](OC4)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@]4(COC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)O3)=C2N=C(NC(C(C)C)=O)N1
  • Molecular Formula
    C45H54N7O9P
  • Molecular Weight
    867.93
  • Appearance
    Off-white to yellow powder,free from visible foreign matter
  • Purity
    HPLC≥98.0%
  • Storage Condition
    -20℃

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With 26+ years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

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Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

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We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.

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