5'-O-DMTr-2'-O-TOM-G(Ac) Phosphoramidite

N2-acetyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-triisopropylsilyloxymethyl-guanosine-Phosphoramidite
Catalog No. PR2-075
Purity HPLC≥98.0%
Molecular Formula C52H72N7O10PSi
Molecular Weight 1014.25
Storage Condition -20℃

5'-O-DMTr-2'-O-TOM-G(Ac) Phosphoramidite

N2-acetyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-triisopropylsilyloxymethyl-guanosine-Phosphoramidite
Grade
SKU: PR2-075
Collections:  2'-O-TOM Phosphoramidites Oligo Synthesis Phosphoramidites Synthesis Blocks
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Specifications
  • Catalog No.
    PR2-075
  • SMILES
    O=C1C2=C(N([C@H]3[C@H](OCO[Si](C(C)C)(C(C)C)C(C)C)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)O3)C=N2)N=C(NC(C)=O)N1
  • Molecular Formula
    C52H72N7O10PSi
  • Molecular Weight
    1014.25
  • Appearance
    White to off-white powder
  • Purity
    HPLC≥98.0%
  • Storage Condition
    -20℃

Documentation
COA Contact Us
  • Catalog No.
    PR2-075
  • SMILES
    O=C1C2=C(N([C@H]3[C@H](OCO[Si](C(C)C)(C(C)C)C(C)C)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)O3)C=N2)N=C(NC(C)=O)N1
  • Molecular Formula
    C52H72N7O10PSi
  • Molecular Weight
    1014.25
  • Appearance
    White to off-white powder
  • Purity
    HPLC≥98.0%
  • Storage Condition
    -20℃

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Integrated Supply & Commercial Scale

With 26+ years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

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Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

Rigorous Quality

We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.

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