Methacrylate C6 Phosphoramidite

6-methacrylamido-hexyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite
Catalog No. OP-162
Purity HPLC≥97%
Molecular Formula C19H36N3O3P
Molecular Weight 385.49

Methacrylate C6 Phosphoramidite

6-methacrylamido-hexyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite
Grade
SKU: OP-162
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Details

The functionality of Methacrylate C6 Phosphoramidite comes from its two key chemical groups:

  • Methacrylate Group: Contains a reactive carbon-carbon double bond that can undergo polymerization reactions, allowing the modified DNA to be incorporated into larger polymer structures.
  • Phosphoramidite Group: This is the standard functionality used in automated solid-phase oligonucleotide synthesis, enabling the precise and sequential addition of the molecule to a growing DNA or RNA chain.

Specifications

  • Catalog No.
    OP-162
  • SMILES
    CC(C(NCCCCCCOP(N(C(C)C)C(C)C)OCCC#N)=O)=C
  • Molecular Formula
    C19H36N3O3P
  • Molecular Weight
    385.49
  • Appearance
    Colorless to light yellow oil, free from visible foreign matter
  • Purity
    HPLC≥97%

Documentation

The functionality of Methacrylate C6 Phosphoramidite comes from its two key chemical groups:

  • Methacrylate Group: Contains a reactive carbon-carbon double bond that can undergo polymerization reactions, allowing the modified DNA to be incorporated into larger polymer structures.
  • Phosphoramidite Group: This is the standard functionality used in automated solid-phase oligonucleotide synthesis, enabling the precise and sequential addition of the molecule to a growing DNA or RNA chain.

Why choose Hongene?

Trusted Partner in Nucleic Acid

Integrated Supply & Commercial Scale

With 26+ years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

Proprietary Technology & IP

Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

Rigorous Quality

We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.

Global Business Network

Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

Global Business Distribution
40+
Countries & Regions
3000≈
Global Clients
54000+L
Annual NTP Production
58+t
Annual Amidites Production

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