5-OMe-UTP 100mM solution
| Catalog No. | R5-046 |
| Purity | HPLC≥97.0% |
| Molecular Formula | C10H14N2Na3O16P3 |
| Molecular Weight | 579.98 |
| Storage Condition | -20℃, Always avoid freeze-thaw cycles. |
| Endotoxin | <1 EU/ml |
5-OMe-UTP 100mM solution
5-OMe-UTP 100mM solution - N (Normal) / 0.1mL / centrifuge tube is backordered and will ship as soon as it is back in stock.
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Shipping notes
Shipping notes
Details
Details
5-methoxy-uridine-5’-triphosphate (5moUTP) is a chemically modified uridine nucleotide designed for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase.
RNAs containing 5moU have been shown to exhibit reduced innate immune activation and altered translational properties compared with unmodified uridine.
The 100 mM disodium salt solution provides 5moU in a highly soluble, ready-to-use form suitable for both routine laboratory applications and high-consistency manufacturing environments.
Applications
Modified mRNA & IVT Research
Used in IVT reactions to produce modified mRNA with altered immunogenic and structural properties compared with unmodified RNA.[1][2]
CRISPR & Genome Editing mRNA
Enables the production of highly active, low-immunogenic Cas9 mRNA for efficient genome editing in vitro and in vivo.[3]
Features
Reference
Specifications
Specifications
-
Catalog No.R5-046R5-046
-
SMILESO=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=OO=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
-
Molecular FormulaC10H14N2Na3O16P3C10H14N2Na3O16P3
-
Molecular Weight579.98579.98
-
AppearanceClear colorless solutionClear colorless solution
-
PurityHPLC≥97.0%HPLC≥97.0%
-
Storage Condition-20℃, Always avoid freeze-thaw cycles.-20℃, Always avoid freeze-thaw cycles.
-
Bacterial Endotoxin Test<1 EU/ml<1 EU/ml
-
Quality ControlThis lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
Documentation
Documentation
5-methoxy-uridine-5’-triphosphate (5moUTP) is a chemically modified uridine nucleotide designed for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase.
RNAs containing 5moU have been shown to exhibit reduced innate immune activation and altered translational properties compared with unmodified uridine.
The 100 mM disodium salt solution provides 5moU in a highly soluble, ready-to-use form suitable for both routine laboratory applications and high-consistency manufacturing environments.
Applications
Modified mRNA & IVT Research
Used in IVT reactions to produce modified mRNA with altered immunogenic and structural properties compared with unmodified RNA.[1][2]
CRISPR & Genome Editing mRNA
Enables the production of highly active, low-immunogenic Cas9 mRNA for efficient genome editing in vitro and in vivo.[3]
Features
Reference
-
Catalog No.R5-046R5-046
-
SMILESO=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=OO=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
-
Molecular FormulaC10H14N2Na3O16P3C10H14N2Na3O16P3
-
Molecular Weight579.98579.98
-
AppearanceClear colorless solutionClear colorless solution
-
PurityHPLC≥97.0%HPLC≥97.0%
-
Storage Condition-20℃, Always avoid freeze-thaw cycles.-20℃, Always avoid freeze-thaw cycles.
-
Bacterial Endotoxin Test<1 EU/ml<1 EU/ml
-
Quality ControlThis lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
Why choose Hongene?
Trusted Partner in Nucleic Acid
Integrated Supply & Commercial Scale
With 26+ years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.
Proprietary Technology & IP
Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.
Rigorous Quality
We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.
Manufacturing Scalability
Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.
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Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.
