GTP, 200mM Tris Salt Solution

Guanosine 5'-triphosphate, tris salt solution
Catalog No. R2-057
Purity HPLC ≥98.0%
Molecular Formula C10H16N5O14P3 (free acid)
Molecular Weight 523.18 (free acid)
Storage Condition -20℃
Endotoxin <1 EU/ml

GTP, 200mM Tris Salt Solution

Guanosine 5'-triphosphate, tris salt solution
Grade
Amount/Package: 1mL / centrifuge tube
SKU: R2-057-ML001-P
Collections:  mRNA NTP Nucleotides Nucleotides for mRNA Other Raw Materials Synthesis Blocks
Unit price:
$36.50

Price

$36.50
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    Details

    Guanosine 5’-triphosphate (GTP) is an essential nucleotide for RNA synthesis and a critical regulator of GTP-binding proteins and translational GTPases.

    This product is supplied as a 200 mM aqueous solution in the Tris salt form, providing a stable, mildly alkaline environment (typically pH 7.5-8.5) that enhances compatibility with biochemical and enzymatic assays.

    Applications

    Reference Standards & Controls

    Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.

    Transcription & RNA Synthesis

    In vitro transcription for synthesis of mRNA, sgRNA, ribozymes, and structured RNAs.

    Signaling & GTPase Biology

    Used to study GTP-binding proteins and translational GTPases.[1][2]

    Features

    High purity, nuclease-free, and extra-low endotoxin: suitable for sensitive biochemical assays.
    Ready-to-use: 200 mM solution eliminates the need for weighing and dissolution.
    Stable disodium salt form: ensures consistent pH and long-term storage.

    Reference

    [1] Takai, Yoshimi, Takuya Sasaki, and Takashi Matozaki. "Small GTP-binding proteins." Physiological reviews 81, no. 1 (2001): 153-208. [2] Maracci, Cristina, and Marina V. Rodnina. "translational GTPases." Biopolymers 105, no. 8 (2016): 463-475.

    Specifications
    • Catalog No.
      R2-057
    • SMILES
      OCC(N)(CO)CO.O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O3)=C2N=C(N)N1
    • Molecular Formula
      C10H16N5O14P3 (free acid)
    • Molecular Weight
      523.18 (free acid)
    • Appearance
      Clear colorless to yellow solution
    • Purity
      HPLC ≥98.0%
    • Storage Condition
      -20℃
    • Bacterial Endotoxin Test
      <1 EU/ml
    • Quality Control
      This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.

    Documentation
    COA Contact Us

    Guanosine 5’-triphosphate (GTP) is an essential nucleotide for RNA synthesis and a critical regulator of GTP-binding proteins and translational GTPases.

    This product is supplied as a 200 mM aqueous solution in the Tris salt form, providing a stable, mildly alkaline environment (typically pH 7.5-8.5) that enhances compatibility with biochemical and enzymatic assays.

    Applications

    Reference Standards & Controls

    Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.

    Transcription & RNA Synthesis

    In vitro transcription for synthesis of mRNA, sgRNA, ribozymes, and structured RNAs.

    Signaling & GTPase Biology

    Used to study GTP-binding proteins and translational GTPases.[1][2]

    Features

    High purity, nuclease-free, and extra-low endotoxin: suitable for sensitive biochemical assays.
    Ready-to-use: 200 mM solution eliminates the need for weighing and dissolution.
    Stable disodium salt form: ensures consistent pH and long-term storage.

    Reference

    [1] Takai, Yoshimi, Takuya Sasaki, and Takashi Matozaki. "Small GTP-binding proteins." Physiological reviews 81, no. 1 (2001): 153-208. [2] Maracci, Cristina, and Marina V. Rodnina. "translational GTPases." Biopolymers 105, no. 8 (2016): 463-475.

    Why choose Hongene?

    Trusted Partner in Nucleic Acid

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    Integrated Supply & Commercial Scale

    With nearly 30 years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

    Proprietary Technology & IP

    Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

    Rigorous Quality

    We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

    Manufacturing Scalability

    Hongene operates a 1.67-million-square-foot oligonucleotide manufacturing facility featuring advanced equipment, including multiple OligoPilot™ and OligoProcess™ synthesizers ranging from 10 to 1,800 mmol. Its 48 flexible production lines enable seamless, one-stop scale-up of API production from gram-level quantities to metric tons, achieving purity of ≥98% while supporting compliance with NMPA, FDA, and EMA regulatory requirements.

    Global Business Network

    Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

    Global Business Distribution
    40+
    Countries & Regions
    ≈3000
    Global Clients
    54000L+
    Annual NTP Production
    58t+
    Annual Amidites Production

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