N1-Me-pUTP, 100mM solution
N1-Me-pUTP, 100mM solution - M (Molecular Biology) / 1mL / centrifuge tube is backordered and will ship as soon as it is back in stock.
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Details
Details
Product Information
N1-Methylpseudouridine-5'-Triphosphate (N1MePsU) is a modified NTP for incorporation into messenger RNAs (mRNA) using an enzyme such as T7 RNA Polymerase.
Modified uridines, including N1-methylpseudouridine, 5-methoxyuridine, and pseudouridine, have been shown to reduce unwanted immunogenic responses and enhance the translational efficiency of mRNAs.
These properties can contribute to the safety of mRNA and the enhancement of protein expression.
Specifications
Specifications
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Catalog No.R5-027R5-027
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CAS No.1428903-59-61428903-59-6
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SMILESO=C(N(C)C=C1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=OO=C(N(C)C=C1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
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Molecular FormulaC10H14N2Na3O15P3C10H14N2Na3O15P3
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Molecular Weight564.13564.13
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AppearanceClear colorless solutionClear colorless solution
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PurityHPLC≥99.0%HPLC≥99.0%
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Storage Condition-20℃, Always avoid freeze-thaw cycles.-20℃, Always avoid freeze-thaw cycles.
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Quality ControlThis lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
Documentation
Documentation
Product Information
N1-Methylpseudouridine-5'-Triphosphate (N1MePsU) is a modified NTP for incorporation into messenger RNAs (mRNA) using an enzyme such as T7 RNA Polymerase.
Modified uridines, including N1-methylpseudouridine, 5-methoxyuridine, and pseudouridine, have been shown to reduce unwanted immunogenic responses and enhance the translational efficiency of mRNAs.
These properties can contribute to the safety of mRNA and the enhancement of protein expression.
-
Catalog No.R5-027R5-027
-
CAS No.1428903-59-61428903-59-6
-
SMILESO=C(N(C)C=C1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=OO=C(N(C)C=C1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O
-
Molecular FormulaC10H14N2Na3O15P3C10H14N2Na3O15P3
-
Molecular Weight564.13564.13
-
AppearanceClear colorless solutionClear colorless solution
-
PurityHPLC≥99.0%HPLC≥99.0%
-
Storage Condition-20℃, Always avoid freeze-thaw cycles.-20℃, Always avoid freeze-thaw cycles.
-
Quality ControlThis lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
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We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.
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Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.
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