2'-O-4'-C-Locked-T Phosphoramidite

5'-O-(4, 4'-dimethoxytrityl)-2'-O-4'-C-Locked-thymidine-3'-cyanoethyl Phosphoramidite

Catalog No.	PR4-001
CAS No.	206055-75-6
Purity	HPLC≥98.0%
Molecular Formula	C₄₁H₄₉N₄O₉P
Molecular Weight	772.83
Storage Condition	-20℃

2'-O-4'-C-Locked-T Phosphoramidite

5'-O-(4, 4'-dimethoxytrityl)-2'-O-4'-C-Locked-thymidine-3'-cyanoethyl Phosphoramidite

Grade

N (Normal)

Amount/Package: 0.25g / 30mL screwed bottle-28

0.25g / 30mL screwed bottle-28

0.5g / 30mL screwed bottle-28

1g / 30mL screwed bottle-28

5g / 240mL screwed bottle

10g / 240mL screwed bottle

25g / 250mL HDPE bottle

100g / 250mL HDPE bottle

200g / 500mL HDPE bottle

Product variants

SKU: PR4-001-025A | suitable for MerMade

Collections: 2'-O-4'-C Locked-NA Phosphoramidites Oligo Synthesis Phosphoramidites Synthesis Blocks

Price

$34.00

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Products on this site:

Currently ship to United States & Canada.

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Processment: within 2 business days, if available.

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Specifications

Catalog No.

PR4-001
PR4-001
PR4-001
PR4-001
PR4-001
PR4-001
PR4-001
PR4-001
CAS No.

206055-75-6
206055-75-6
206055-75-6
206055-75-6
206055-75-6
206055-75-6
206055-75-6
206055-75-6
SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
Molecular Formula

C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
Molecular Weight

772.83
772.83
772.83
772.83
772.83
772.83
772.83
772.83
Appearance

Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Purity

HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
Storage Condition

-20℃
-20℃
-20℃
-20℃
-20℃
-20℃
-20℃
-20℃
Moisture Content

K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w

Documentation

COA Contact Us

Catalog No.

PR4-001
PR4-001
PR4-001
PR4-001
PR4-001
PR4-001
PR4-001
PR4-001
CAS No.

206055-75-6
206055-75-6
206055-75-6
206055-75-6
206055-75-6
206055-75-6
206055-75-6
206055-75-6
SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@@]1(COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO2
Molecular Formula

C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
C₄₁H₄₉N₄O₉P
Molecular Weight

772.83
772.83
772.83
772.83
772.83
772.83
772.83
772.83
Appearance

Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Off-white to yellow powder,free from visible foreign matter
Purity

HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
HPLC≥98.0%
Storage Condition

-20℃
-20℃
-20℃
-20℃
-20℃
-20℃
-20℃
-20℃
Moisture Content

K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w
K.F.≤0.50% w/w

Why choose Hongene?

Trusted Partner in Nucleic Acid

Integrated Supply & Commercial Scale

With 26+ years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

Proprietary Technology & IP

Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

Rigorous Quality

We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.

Global Business Network

Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

Global Business Distribution

40+

Countries & Regions

3000≈

Global Clients

54000+L

Annual NTP Production

58+t

Annual Amidites Production