5-OMe UTP, 200mM Tris Salt Solution
| Catalog No. | R5-066 |
| Purity | HPLC ≥97% |
| Molecular Formula | C10H17N2O16P3 (free acid) |
| Molecular Weight | 514.17 (free acid) |
| Storage Condition | -20℃ |
| Endotoxin | <1 EU/ml |
5-OMe UTP, 200mM Tris Salt Solution
5-OMe UTP, 200mM Tris Salt Solution - M (Molecular Biology)+S (Endotoxin) / 0.1mL / centrifuge tube is backordered and will ship as soon as it is back in stock.
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Shipping notes
Shipping notes
Details
Details
5-methoxy-uridine-5’-triphosphate (5moUTP) is a chemically modified uridine nucleotide designed for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase.
RNAs containing 5moU have been shown to exhibit reduced innate immune activation and altered translational properties compared with unmodified uridine.
This product is supplied as a 200 mM aqueous solution in the Tris salt form, providing a stable, mildly alkaline environment (typically pH 7.5-8.5) that enhances compatibility with biochemical and enzymatic assays.
Applications
Modified mRNA & IVT Research
Used in IVT reactions to produce modified mRNA with altered immunogenic and structural properties compared with unmodified RNA.[1][2]
CRISPR & Genome Editing mRNA
Enables the production of highly active, low-immunogenic Cas9 mRNA for efficient genome editing in vitro and in vivo.[3]
Features
Reference
Specifications
Specifications
-
Catalog No.R5-066R5-066
-
SMILESOCC(N)(CO)CO.O=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O2)NC1=OOCC(N)(CO)CO.O=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O2)NC1=O
-
Molecular FormulaC10H17N2O16P3 (free acid)C10H17N2O16P3 (free acid)
-
Molecular Weight514.17 (free acid)514.17 (free acid)
-
AppearanceClear colorless to yellow solutionClear colorless to yellow solution
-
PurityHPLC ≥97%HPLC ≥97%
-
Storage Condition-20℃-20℃
-
Bacterial Endotoxin Test<1 EU/ml<1 EU/ml
-
Quality ControlThis lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
Documentation
Documentation
5-methoxy-uridine-5’-triphosphate (5moUTP) is a chemically modified uridine nucleotide designed for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase.
RNAs containing 5moU have been shown to exhibit reduced innate immune activation and altered translational properties compared with unmodified uridine.
This product is supplied as a 200 mM aqueous solution in the Tris salt form, providing a stable, mildly alkaline environment (typically pH 7.5-8.5) that enhances compatibility with biochemical and enzymatic assays.
Applications
Modified mRNA & IVT Research
Used in IVT reactions to produce modified mRNA with altered immunogenic and structural properties compared with unmodified RNA.[1][2]
CRISPR & Genome Editing mRNA
Enables the production of highly active, low-immunogenic Cas9 mRNA for efficient genome editing in vitro and in vivo.[3]
Features
Reference
-
Catalog No.R5-066R5-066
-
SMILESOCC(N)(CO)CO.O=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O2)NC1=OOCC(N)(CO)CO.O=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O2)NC1=O
-
Molecular FormulaC10H17N2O16P3 (free acid)C10H17N2O16P3 (free acid)
-
Molecular Weight514.17 (free acid)514.17 (free acid)
-
AppearanceClear colorless to yellow solutionClear colorless to yellow solution
-
PurityHPLC ≥97%HPLC ≥97%
-
Storage Condition-20℃-20℃
-
Bacterial Endotoxin Test<1 EU/ml<1 EU/ml
-
Quality ControlThis lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
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