5-OMe UTP, 200mM Tris Salt Solution
| Catalog No. | R5-066 |
| Purity | HPLC≥97.0% |
| Molecular Formula | C10H18N3O14P3 (free acid) |
| Molecular Weight | 497.18 (free acid) |
| Storage Condition | -20℃, Always avoid freeze-thaw cycles. |
5-OMe UTP, 200mM Tris Salt Solution
5-OMe UTP, 200mM Tris Salt Solution - M (Molecular Biology)+S (Endotoxin) / 0.1mL / centrifuge tube is backordered and will ship as soon as it is back in stock.
Couldn't load pickup availability
Shipping notes
Shipping notes
Details
Details
5-methoxy-uridine-5’-triphosphate (5moUTP) is a chemically modified uridine nucleotide designed for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase.
RNAs containing 5moU have been shown to exhibit reduced innate immune activation and altered translational properties compared with unmodified uridine.
This product is supplied as a 200 mM aqueous solution in the Tris salt form, providing a stable, mildly alkaline environment (typically pH 7.5-8.5) that enhances compatibility with biochemical and enzymatic assays.
Applications
Modified mRNA & IVT Research
Used in IVT reactions to produce modified mRNA with altered immunogenic and structural properties compared with unmodified RNA.[1][2]
CRISPR & Genome Editing mRNA
Enables the production of highly active, low-immunogenic Cas9 mRNA for efficient genome editing in vitro and in vivo.[3]
Features
Reference
Specifications
Specifications
-
Catalog No.R5-066R5-066
-
SMILESOCC(N)(CO)CO.O=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O2)NC1=OOCC(N)(CO)CO.O=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O2)NC1=O
-
Molecular FormulaC10H18N3O14P3 (free acid)C10H18N3O14P3 (free acid)
-
Molecular Weight497.18 (free acid)497.18 (free acid)
-
AppearanceClear colorless to yellow solutionClear colorless to yellow solution
-
PurityHPLC≥97.0%HPLC≥97.0%
-
Storage Condition-20℃, Always avoid freeze-thaw cycles.-20℃, Always avoid freeze-thaw cycles.
-
Bacterial Indotocxin Test<1 EU/ml<1 EU/ml
-
Quality ControlThis lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
Documentation
Documentation
5-methoxy-uridine-5’-triphosphate (5moUTP) is a chemically modified uridine nucleotide designed for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase.
RNAs containing 5moU have been shown to exhibit reduced innate immune activation and altered translational properties compared with unmodified uridine.
This product is supplied as a 200 mM aqueous solution in the Tris salt form, providing a stable, mildly alkaline environment (typically pH 7.5-8.5) that enhances compatibility with biochemical and enzymatic assays.
Applications
Modified mRNA & IVT Research
Used in IVT reactions to produce modified mRNA with altered immunogenic and structural properties compared with unmodified RNA.[1][2]
CRISPR & Genome Editing mRNA
Enables the production of highly active, low-immunogenic Cas9 mRNA for efficient genome editing in vitro and in vivo.[3]
Features
Reference
-
Catalog No.R5-066R5-066
-
SMILESOCC(N)(CO)CO.O=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O2)NC1=OOCC(N)(CO)CO.O=C(C(OC)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O2)NC1=O
-
Molecular FormulaC10H18N3O14P3 (free acid)C10H18N3O14P3 (free acid)
-
Molecular Weight497.18 (free acid)497.18 (free acid)
-
AppearanceClear colorless to yellow solutionClear colorless to yellow solution
-
PurityHPLC≥97.0%HPLC≥97.0%
-
Storage Condition-20℃, Always avoid freeze-thaw cycles.-20℃, Always avoid freeze-thaw cycles.
-
Bacterial Indotocxin Test<1 EU/ml<1 EU/ml
-
Quality ControlThis lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
Why choose Hongene?
Trusted Partner in Nucleic Acid
Integrated Supply & Commercial Scale
With 26+ years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.
Proprietary Technology & IP
Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.
Rigorous Quality
We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.
Manufacturing Scalability
Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.
Global Business Network
Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.
