GTP 100mM solution

Guanosine-5'-triphosphate, trisodium salt

Catalog No.	R2331
CAS No.	36051-31-7
Purity	HPLC≥99.0%
Molecular Formula	C₁₀H₁₃N₅Na₃O₁₄P₃
Molecular Weight	589.13
Storage Condition	-20℃, Always avoid freeze-thaw cycles.

GTP 100mM solution

Guanosine-5'-triphosphate, trisodium salt

Grade

M (Molecular Biology) S (Endotoxin)

Amount/Package: 1mL / centrifuge tube

1mL / centrifuge tube

5mL / nalgene bottle

Product variants

SKU: R2331-ML001-P

Collections: Diagnostics mRNA NTP NTP for Diagnostics Nucleotides Nucleotides for Diagnostics Nucleotides for mRNA Other Raw Materials Synthesis Blocks

Price

$17.50

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Details

Guanosine 5’-triphosphate (GTP) is an essential nucleotide for RNA synthesis and a critical regulator of GTP-binding proteins and translational GTPases.

This 100 mM trisodium salt solution provides GTP in a highly soluble, ready-to-use form suitable for both routine laboratory applications and high-consistency manufacturing environments.

Applications

Reference Standards & Controls

Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.

Trascription & RNA Synthesis

In vitro transcription for synthesis of mRNA, sgRNA, ribozymes, and structured RNAs.

Signaling & GTPase Biology

Used to study GTP-binding proteins and translational GTPases.^[1][2]

Features and Benefits

High purity(≥99%), nuclease-free, and Ultra-low endotoxin: suitable for sensitive biochemical assays.

Ready-to-use: 100 mM solution eliminates the need for weighing and dissolution.

Stable disodium salt form: ensures consistent pH and long-term storage.

Reference

[1] Takai, Yoshimi, Takuya Sasaki, and Takashi Matozaki. "Small GTP-binding proteins." Physiological reviews 81, no. 1 (2001): 153-208. [2] Maracci, Cristina, and Marina V. Rodnina. "translational GTPases." Biopolymers 105, no. 8 (2016): 463-475.

Specifications

Catalog No.

R2331
R2331
R2-039
CAS No.

36051-31-7
36051-31-7
36051-31-7
SMILES

O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O3)=C2N=C(N)N1
O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O3)=C2N=C(N)N1
O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O3)=C2N=C(N)N1
Molecular Formula

C₁₀H₁₃N₅Na₃O₁₄P₃
C₁₀H₁₃N₅Na₃O₁₄P₃
C₁₀H₁₃N₅Na₃O₁₄P₃
Molecular Weight

589.13
589.13
589.13
Appearance

Clear colorless solution
Clear colorless solution
Clear colorless solution
Purity

HPLC≥99.0%
HPLC≥99.0%
HPLC≥99.0%
Storage Condition

-20℃, Always avoid freeze-thaw cycles.
-20℃, Always avoid freeze-thaw cycles.
-20℃, Always avoid freeze-thaw cycles.
Quality Control

This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.

Documentation

COA Contact Us

Guanosine 5’-triphosphate (GTP) is an essential nucleotide for RNA synthesis and a critical regulator of GTP-binding proteins and translational GTPases.

This 100 mM trisodium salt solution provides GTP in a highly soluble, ready-to-use form suitable for both routine laboratory applications and high-consistency manufacturing environments.

Applications

Reference Standards & Controls

Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.

Trascription & RNA Synthesis

In vitro transcription for synthesis of mRNA, sgRNA, ribozymes, and structured RNAs.

Signaling & GTPase Biology

Used to study GTP-binding proteins and translational GTPases.^[1][2]

Features and Benefits

High purity(≥99%), nuclease-free, and Ultra-low endotoxin: suitable for sensitive biochemical assays.

Ready-to-use: 100 mM solution eliminates the need for weighing and dissolution.

Stable disodium salt form: ensures consistent pH and long-term storage.

Reference

Catalog No.

R2331
R2331
R2-039
CAS No.

36051-31-7
36051-31-7
36051-31-7
SMILES

O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O3)=C2N=C(N)N1
O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O3)=C2N=C(N)N1
O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O3)=C2N=C(N)N1
Molecular Formula

C₁₀H₁₃N₅Na₃O₁₄P₃
C₁₀H₁₃N₅Na₃O₁₄P₃
C₁₀H₁₃N₅Na₃O₁₄P₃
Molecular Weight

589.13
589.13
589.13
Appearance

Clear colorless solution
Clear colorless solution
Clear colorless solution
Purity

HPLC≥99.0%
HPLC≥99.0%
HPLC≥99.0%
Storage Condition

-20℃, Always avoid freeze-thaw cycles.
-20℃, Always avoid freeze-thaw cycles.
-20℃, Always avoid freeze-thaw cycles.
Quality Control

This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.
This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.

Why choose Hongene?

Trusted Partner in Nucleic Acid

Integrated Supply & Commercial Scale

With nearly 30 years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

Proprietary Technology & IP

Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

Rigorous Quality

We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.

Global Business Network

Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

Global Business Distribution

40+

Countries & Regions

3000≈

Global Clients

54000+L

Annual NTP Production

58+t

Annual Amidites Production