IJM Nanoproducer
IJM Nanoproducer - Pilot to large-scale is backordered and will ship as soon as it is back in stock.
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Customized impingement jets mixing skid for Large Production Scale.

Production-scale Impingement Jets Mixing (IJM) Skid for the high flow production of lipid nanoparticles (LNP, microemulsions, etc.)
The Impingement Jets Mixing (IJM) Large Production Scale Units for high flow production of nanoparticles (LNP, microemulsions, etc.) can be configured with up to eight parallel mixing units depending on customer requirements. Each unit consists of two pumps to deliver lipid and API streams, two flowmeters for flow control, and one jet mixer.
Depending on the configuration, the predilution of the API and quenching can be performed for the combined flow of all units in one process step outside the Impingement Jets Mixing (IJM) Production Scale Unit.
The number of parallel units depends on the application. Also, the number of pumps, flowmeters, jets mixers, and pipes can be adapted to the required conditions and scale. All skids are built in a stainless steel frame on casters and are suitable for CIP cleaning procedures in pharmaceutical production.
The Impingement Jets Mixing (IJM) Large Production Scale Unit for high flow production of nanoparticles (LNP, microemulsions, etc.) consisting of:
In addition, we offer for our customers:
Specifications
Specifications
-
Catalog No.DV-02
-
RemarksPilot to large-scale

Customized impingement jets mixing skid for Large Production Scale.

Production-scale Impingement Jets Mixing (IJM) Skid for the high flow production of lipid nanoparticles (LNP, microemulsions, etc.)
The Impingement Jets Mixing (IJM) Large Production Scale Units for high flow production of nanoparticles (LNP, microemulsions, etc.) can be configured with up to eight parallel mixing units depending on customer requirements. Each unit consists of two pumps to deliver lipid and API streams, two flowmeters for flow control, and one jet mixer.
Depending on the configuration, the predilution of the API and quenching can be performed for the combined flow of all units in one process step outside the Impingement Jets Mixing (IJM) Production Scale Unit.
The number of parallel units depends on the application. Also, the number of pumps, flowmeters, jets mixers, and pipes can be adapted to the required conditions and scale. All skids are built in a stainless steel frame on casters and are suitable for CIP cleaning procedures in pharmaceutical production.
The Impingement Jets Mixing (IJM) Large Production Scale Unit for high flow production of nanoparticles (LNP, microemulsions, etc.) consisting of:
In addition, we offer for our customers:
-
Catalog No.DV-02
-
RemarksPilot to large-scale
Why choose Hongene?
Trusted Partner in Nucleic Acid
Integrated Supply & Commercial Scale
With 26+ years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.
Proprietary Technology & IP
Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.
Rigorous Quality
We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.
Manufacturing Scalability
Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.
Global Business Network
Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

