UTP, 200mM Tris Salt Solution

Uridine 5'-triphosphate, tris salt solution
Catalog No. R5-065
Purity HPLC≥97.0%
Molecular Formula C9H15N2O15P3 (free acid)
Molecular Weight 484.14 (free acid)
Storage Condition -20℃, Always avoid freeze-thaw cycles.

UTP, 200mM Tris Salt Solution

Uridine 5'-triphosphate, tris salt solution
Grade
Amount/Package: 1mL / centrifuge tube
SKU: R5-065-ML001-P
Collections:  mRNA NTP Nucleotides Nucleotides for mRNA Other Raw Materials Synthesis Blocks
Unit price:
$36.50

Price

$36.50
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Currently ship to United States & Canada.
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Details

Uridine 5’-triphosphate (UTP) is used for RNA synthesis and serves as a precursor for a variety of nucleotide-sugar derivatives used in glycosylation pathways.

This product is supplied as a 200 mM aqueous solution in the Tris salt form, providing a stable, mildly alkaline environment (typically pH 7.5-8.5) that enhances compatibility with biochemical and enzymatic assays.

Applications

Reference Standards & Controls

Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.

Transcription & RNA Synthesis

In vitro transcription for synthesis of mRNA, sgRNA, ribozymes, and structured RNAs.

Cell Signaling & Receptor Biology

Purinergic signaling studies involving UTP-responsive P2Y receptors.[1][2]

Features

High purity, nuclease-free, and extra-low endotoxin: suitable for sensitive biochemical assays.
Ready-to-use: 200 mM solution eliminates the need for weighing and dissolution.
Stable disodium salt form: ensures consistent pH and long-term storage.

Reference

[1] Stucky, Cheryl L., Karen A. Medler, and Derek C. Molliver. "The P2Y agonist UTP activates cutaneous afferent fibers." Pain 109, no. 1-2 (2004): 36-44. [2] Choi, Roy CY, Glanice KY Chu, Nina L. Siow, Amanda WY Yung, Lisa Y. Yung, Pinky SC Lee, Christopher CW Lo et al. "Activation of UTP-sensitive P2Y2 receptor induces the expression of cholinergic genes in cultured cortical neurons: a signaling cascade triggered by Ca2+ mobilization and extracellular regulated kinase phosphorylation." Molecular Pharmacology 84, no. 1 (2013): 50-61.

Specifications
  • Catalog No.
    R5-065
  • SMILES
    OCC(N)(CO)CO.O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O2)NC1=O
  • Molecular Formula
    C9H15N2O15P3 (free acid)
  • Molecular Weight
    484.14 (free acid)
  • Appearance
    Clear colorless to yellow solution
  • Purity
    HPLC≥97.0%
  • Storage Condition
    -20℃, Always avoid freeze-thaw cycles.
  • Bacterial Indotocxin Test
    <1 EU/ml
  • Quality Control
    This lot of NTP has been performance tested in transcription reaction. This preparation is free of DNase and RNase contamination.

Documentation
COA Contact Us

Uridine 5’-triphosphate (UTP) is used for RNA synthesis and serves as a precursor for a variety of nucleotide-sugar derivatives used in glycosylation pathways.

This product is supplied as a 200 mM aqueous solution in the Tris salt form, providing a stable, mildly alkaline environment (typically pH 7.5-8.5) that enhances compatibility with biochemical and enzymatic assays.

Applications

Reference Standards & Controls

Serves as a quantitative standard for HPLC, LC–MS, enzyme kinetics, and calibration of nucleotide quantification assays.

Transcription & RNA Synthesis

In vitro transcription for synthesis of mRNA, sgRNA, ribozymes, and structured RNAs.

Cell Signaling & Receptor Biology

Purinergic signaling studies involving UTP-responsive P2Y receptors.[1][2]

Features

High purity, nuclease-free, and extra-low endotoxin: suitable for sensitive biochemical assays.
Ready-to-use: 200 mM solution eliminates the need for weighing and dissolution.
Stable disodium salt form: ensures consistent pH and long-term storage.

Reference

[1] Stucky, Cheryl L., Karen A. Medler, and Derek C. Molliver. "The P2Y agonist UTP activates cutaneous afferent fibers." Pain 109, no. 1-2 (2004): 36-44. [2] Choi, Roy CY, Glanice KY Chu, Nina L. Siow, Amanda WY Yung, Lisa Y. Yung, Pinky SC Lee, Christopher CW Lo et al. "Activation of UTP-sensitive P2Y2 receptor induces the expression of cholinergic genes in cultured cortical neurons: a signaling cascade triggered by Ca2+ mobilization and extracellular regulated kinase phosphorylation." Molecular Pharmacology 84, no. 1 (2013): 50-61.

Why choose Hongene?

Trusted Partner in Nucleic Acid

Integrated Supply & Commercial Scale

With 26+ years of expertise, we control a secure supply chain for RNA raw materials and provide reliable GMP-grade oligo synthesis from research to commercial kilogram-scale production.

Proprietary Technology & IP

Our proprietary Chemoenzymatic Ligation Platform combines chemical andenzymatic methods, enabling high-putity, cost-effective, and large-scale production of RNA-based therapeutics.

Rigorous Quality

We implement multiple stringent QC steps, maintain ISO certifications, and ensure >99% batch-to-batch consistency, reducing scale-up and PPQ risks.

Manufacturing Scalability

Hongene operates 1.67 million sq. ft Oligonucleotide Manufacturing Facility, with advanced equipments including multiple OligoPilot™ and OligoProcess™ synthesizers (10-1800 mmol). 48 flexible production lines enable one-stop seamless scaling-up of API production from gram-level to tons and acheive high purity of 98%, meeting NMPA, FDA, and EMA standards.

Global Business Network

Our products and services reach over 40 countries and regions, supporting around 3,000 clients worldwide.

Global Business Distribution
40+
Countries & Regions
3000≈
Global Clients
54000+L
Annual NTP Production
58+t
Annual Amidites Production

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